Treatment of Severe Dyslipoproteinemia in the Prevention of Coronary Heart Disease: 3rd International Symposium, Munich, October 1990

Are serum triglycerides atherogenic? At least in familial dysbetalipoproteinemia, familial combined hyperlipidemia and chylomicronemia, triglyceride-rich lipoproteins have been proven to cause premature atherosclerosis. Not only these lipoprotein disorders are discussed in detail, but also other hypertriglyceridemic disorders are reviewed, including dietary and drug treatment. Insights in the development of atherosclerosis are the basis in evaluating therapeutic principles in the prevention of coronary heart disease. Topics of this book include evolution and progression of atherosclerotic lesions in the first forty years of life. Lipoproteins and atheroma formation, the role of macrophages, platelets and prostaglandins and the special situation in diabetes mellitus are reviewed as well. The knowledge about drug treatment of severe hypercholesterolemia and LDL apheresis is updated. Read more